- FDA Says it’s Seized ‘Thousands of Units’ of Counterfeit Ozempic FDA
- Unhappy or Anxious? How You Sleep May be the Cause
- This Raphael Masterpiece isn’t Quite What it Seems
- Starbucks’ CEO Wants People to Stop Protesting its Stores over Israel War in Gaza
- Cancer-fighting CAR-T cells could be Made Inside Body with Viral Injection
- Polar Bear Fur-inspired Sweater is Thinner Than a Down Jacket — and Just as Warm
FDA Says it’s Seized ‘Thousands of Units’ of Counterfeit Ozempic FDA
稱已查獲「數千件」假冒 Ozempic
Health
The US Food and Drug Administration warned Thursday that it’s seized “thousands of units” of counterfeit versions of the type 2 diabetes drug Ozempic from the US drug supply chain, and it’s urging suppliers, pharmacies and patients to use caution. Five people have gotten sick in connection with the products, but none of the cases has been serious, the FDA said. The FDA warns pharmacies, health care systems, wholesalers and patients to double-check their semaglutide products to make sure they are the real thing. One-milligram injectable Ozempic products with the lot number NAR0074 and serial number 430834149057 on the box should not be used. The agency and drugmaker Novo Nordisk are testing the fakes to determine whether they’re dangerous and to identify what the substance is. The pen label, carton, information for patients and health care professionals, and needles that come with the injectors are also counterfeit, the FDA said. The needles’ sterility can’t be confirmed, so using them could lead to infection.
--from CNN
美國食品和藥物管理局週四警告說，它從美國藥品供應鏈中查獲了「數千單位」的假冒 二型糖尿病藥物 Ozempic，並敦促供應商、藥房和患者謹慎使用。 FDA 表示，已有5人因使用這些產品而生病，但尚未有嚴重病例。 FDA 警告藥局、醫療保健系統、批發商和患者仔細檢查他們的semaglutide產品，以確保它們是正品。 不應使用包裝盒上批號為 NAR0074、序號為 430834149057 的 1 毫克注射劑 Ozempic 產品。 該機構和製藥商Novo Nordisk正在測試這些假貨，以確定它們是否危險並確定其成分是什麼。 FDA 表示，注射器附帶的筆標籤、紙盒、患者和醫療保健專業人員的資訊以及注射器附帶的針頭也是假冒的。 無法確認針頭是否無菌，因此使用它們可能會導致感染。
-- 摘錄翻譯自 CNN
Unhappy or Anxious? How You Sleep May be the Cause
不高興還是焦慮？ 你的睡眠方式可能是原因
Health
Not getting enough sleep or sleeping poorly can greatly affect your mood and mental health, according to a new study analyzing 50 years of research. Cameron Diaz: ‘We should normalize separate bedrooms’ “We found that all forms of sleep loss — total sleep deprivation, partial sleep loss, and sleep fragmentation — resulted in emotional changes. The strongest and most consistent effect was that sleep loss reduced positive mood,” said co-lead author Cara Palmer, assistant professor and director of the Sleep and Development Lab at Montana State University in Bozeman. “We also found that sleep loss increased feelings of anxiety,” Palmer said in an email. “When experiencing emotional events, people were also more likely to report reacting differently than people who were well-rested. “Specifically, they reported feeling less emotional arousal, which is when we feel the intensity of certain emotions in our body, suggesting that overall people felt more muted emotional responses after sleep loss.”
--from CNN
一項針對 50 年研究進行分析的新研究表明，睡眠不足或睡眠品質不佳，會嚴重影響您的情緒和心理健康。 Cameron Diaz：「我們應該規劃單獨的臥室」 「我們發現所有形式的睡眠不足—完全睡眠不足、部分睡眠不足和睡眠片段化—都會導致情緒變化。 最強烈和最一致的影響是睡眠不足降低了積極情緒，」共同主要作者、蒙大拿州立大學Bozeman分校睡眠與發展實驗室助理教授兼主任Cara Palmer說。 「我們還發現睡眠不足會增加焦慮感，」Palmer在一封電子郵件中說。 「當經歷情緒事件時，睡眠不足人們也更有可能表現出與休息良好的人不同的反應。 「具體而言，他們報告說，當我們感受到體內某些情緒的強度時，他們的情緒喚起程度較低，這表明總體來說，人們在睡眠不足後感受到的情緒反應更加弱化。」
--摘錄翻譯自CNN
This Raphael Masterpiece isn’t Quite What it Seems
這幅拉斐爾的傑作並不完全是看起來的那樣
Culture
A 500-year-old Raphael painting is partially the work of another artist, according to a new study. A team led by scientists from England’s University of Bradford used artificial intelligence to determine that the face of Joseph in the “Madonna della Rosa” (“Madonna of the Rose”) was painted by someone other than the Renaissance master. Raphael is one of the best known Renaissance masters and lived from 1483 to 1520. The Italian is best known for works such as “The School of Athens” and “Three Graces.” Hassan Ugail, director of the Centre for Visual Computing and Intelligent Systems at the University of Bradford, told CNN Thursday that he’d developed an algorithm to recognize genuine Raphael paintings, with 98% accuracy. It analyzes 4,000 parameters such as brush strokes, color palette and hue to determine whether a painting is a genuine Raphael, explained Ugail. “Madonna della Rosa,” which hangs in the Museo del Prado in Madrid, has long been subject to debate, said study co-author Howell Edwards, emeritus professor of molecular spectroscopy at the University of Bradford, in a press release.
-- from CNN
一項新的研究表明，一幅 500 年歷史的Raphael畫作部分是另一位藝術家的作品。 英國Bradford大學科學家領導的團隊利用人工智慧來確定《Madonna della Rosa》中Joseph的臉是由文藝復興大師以外的人所畫的。 Raphael (1483-1520) 是文藝復興時期最著名的大師之一。這位義大利人以《The School of Athens》和《Three Graces》等作品而聞名。 Bradford大學視覺計算和智慧系統中心主任Hassan Ugail週四告訴 CNN，他開發了一種演算法來識別真正的Raphael畫作，準確率高達 98%。 Ugail 解釋說，演算法會分析 4000 個參數，例如筆觸、調色板和色調，以確定一幅畫是否是真正的Raphael作品。 該研究的合著者、Bradford大學分子光譜學榮譽教授Howell Edwards在新聞稿中表示，掛在馬德里Museo del Prado的《Madonna della Rosa》長期以來一直受到爭議。
--摘錄翻譯自CNN
Starbucks’ CEO Wants People to Stop Protesting its Stores over Israel War in Gaza
星巴克執行長希望人們停止因以色列在加沙發動戰爭而抗議門市
Culture
Starbucks chief executive Laxman Narasimhan on Tuesday said people protesting the company and disrupting its stores over the Israel-Hamas war were being misled by false information spread online about the company’s positions. “We see protestors influenced by misrepresentation on social media of what we stand for,” Narasimhan said in a letter to Starbucks employees and customers. “Cities around the world – including here in North America – have seen escalating protests. Many of our stores have experienced incidents of vandalism,” he said. “We have worked with local authorities to ensure our partners and customers are safe.” The letter is a way of attempting to untangle Starbucks from controversies related to the war. Starbucks has also tried to distance itself from pro-Palestine positions taken by Starbucks Workers United, a union for Starbucks workers, that have angered some pro-Israel supporters.
--from CNN
星巴克執行長Laxman Narasimhan 週二表示，因以色列與哈瑪斯戰爭而抗議該公司並擾亂其門店的人們，是因為受到了網上傳播關於該公司立場的虛假信息誤導。 Narasimhan在給星巴克員工和顧客的一封信中表示：「我們看到抗議者受到社交媒體上對我們立場歪曲言論的影響。」 「世界各地的城市—包括北美—抗議活動不斷升級。我們的許多商店都遭遇到續意破壞事件，」他說。 「我們已與地方當局合作，確保我們的合作夥伴和客戶的安全。」 這封信是試圖讓星巴克擺脫與戰爭有關的爭議的一種方式。 星巴克也試圖與星巴克工人工會—星巴克工人聯合會所採取的親巴勒斯坦立場保持距離，因為這些立場激怒了一些親以色列的支持者。
--摘錄翻譯自CNN
Cancer-fighting CAR-T cells could be Made Inside Body with Viral Injection
可以透過病毒注射在體內製造抗癌 CAR-T 細胞
Sciences
Researchers are closing in on ways to produce CAR T cells in the body, raising hopes that the notoriously expensive and bespoke cancer therapies might one day become more accessible. In CAR-T treatment, immune cells called T cells are removed from the person receiving treatment, engineered to target cancer cells and reintroduced to their body. The process has yielded dramatic recoveries from advanced forms of some blood cancers, but its high price and technical difficulty have placed it out of reach for many people. Results presented at the American Society of Hematology annual meeting in San Diego, California on 11 December suggest that people undergoing treatment might eventually just get an injection of a virus that infects T cells. The virus would then insert the genes needed to guide the T cells to tumour cells. ”You don’t need to take the cells out, you don’t need to purify them,” says John DiPersio, a transplant immunologist and oncologist at Washington University in St. Louis, Missouri, who says that he was sceptical that the approach would work until he heard the talks at the meeting. ”They convinced me that it’s possible.”
--from Nature
研究人員正在加緊研究在體內生產 CAR T 細胞的方法，這讓人們燃起了希望，因為這種眾所周知昂貴且定制的癌症療法，有一天可能會變得更容易獲得。 在 CAR-T 治療中，被稱為 T 細胞的免疫細胞從接受治療的人體內取出，經過改造以靶向癌細胞，然後重新引入患者體內。 這個過程使一些晚期血癌獲得了顯著的康復，但其高昂的價格和技術難度使許多人無法承受。 12 月 11 日在加州San Diego舉行的美國血液學會年會上公佈的研究結果表明，或許接受治療的人未來可能只需注射可以感染 T 細胞的病毒。 然後病毒會插入引導 T 細胞到達腫瘤細胞所需的基因。 密蘇里州聖路易斯Washington大學的移植免疫學家和腫瘤學家John DiPersio 說：「你不需要取出細胞，也不需要純化它們。」他表示，他對這種方法持懷疑態度，直到他聽到會議上的演講為止。 「他們讓我相信這是可能的。」
--摘錄翻譯自Nature
Polar Bear Fur-inspired Sweater is Thinner Than a Down Jacket — and Just as Warm
北極熊毛衣比羽絨外套更薄，但同樣保暖
Sciences
A sweater knitted from a fibre that mimics polar bear fur offers as much warmth as a down jacket, despite being one-fifth as thick, according to a study published today in Science. The fibre — made from a light, synthetic material known as an aerogel — maintains its heat-trapping properties even after being stretched, washed and dyed. The proof-of-concept fibre might one day be used for clothing that need to be lightweight and durable — such as sportswear, military uniforms and spacesuits — without the need for animal fur or down, says study co-author Weiwei Gao, a materials scientist at Zhejiang University in China. Studies have found that aerogels are among the best heat-locking materials around, and they have been used as insulation in buildings. But fibres made from aerogels are often too brittle and fragile to be weaved into wearable textiles, and they tend to lose their insulating properties after washing and in humid environments.
--from Nature
根據《Science》今天發表的一項研究，由模仿北極熊皮毛的纖維編織而成的毛衣提供了與羽絨服一樣的保暖性，儘管其厚度只有羽絨外套的五分之一。 這種纖維由一種稱為氣凝膠(aerogel)的輕質合成材料製成，即使在拉伸、洗滌和染色後也能保持其蓄熱的性能。 在中國Zhejiang大學科學家，也是研究的合著者Weiwei Gau 表示，這種概念驗證纖維有一天可能會用於需要輕便耐用的服裝，例如運動服、軍裝和宇航服，而不需要動物毛皮或羽絨。 研究發現，氣凝膠是最好的熱鎖材料之一，它們已被用作建築物的隔熱材料。 但氣凝膠製成的纖維通常太脆，無法織成可穿戴的紡織品，而且在洗滌後和潮濕環境中，它們往往會失去絕緣性能。
--摘錄翻譯自Nature